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*Wound Management nishitarumizu        2000.9.19 ***I. General Principles     The goal of wound management is primarily restoration of function, which requires minimizing    risk of infection and repair of injured tissue with a minimum of cosmetic deformity. Be sure to    maintain universal precautions.   ***II. Significant History   A. Mechanism of injury.      1.Blunt trauma. Split or crush type of injuries will swell more and tend to have more       devitalized tissue and a higher risk of infection.      2.Sharp trauma. Clean edges, low cellular injury, and risk of infection.      3.Puncture wounds.      4.Bite injury.   B.Contaminants.      Wound contact with manure, rust, dirt, etc., will increase risk of infection.      Wounds sustained in barnyards or stables are considered contaminated.      Clostridium tetani is indigenous in manure.   C.Time of injury.      After 3 hours, the bacterial count in a wound increases dramatically.Wounds may be closed       primarily up to 12-18 hours out; clean well and use clinical judgment when choosing which       wounds to close.      Wounds up to 24 hours old on the face may be closed after good cleaning. The blood supply      in this area is much better and the risk of infection therefore much less.      The risk of infection may be reduced in wounds by use of tape closures (such as Steri-Strip      tape).   D.[[Tetanus status(http://homepages.go.com/homepages/a/n/e/anealkhan/tetanus_prophylaxis.htm)>http://homepages.go.com/homepages/a/n/e/anealkhan/tetanus_prophylaxis.htm]]   E.Other medical illnesses.      Diabetes, chemotherapy, steroids, peripheral vascular disease, and malnutrition may delay      wound healing and increase the risk of infection.   ***III.Physical Exam     A.Vascular injury.        Direct pressure is the first choice for controlling bleeding.        If a fracture is involved, immobilization will help control bleeding. Do not clamp        vascular structures until it is determined if it is a significant vessel needing repair.        If the anatomy is suspicious for injury to major vascular structures, obtain angiogram        and consider surgical consult. Capillary refill should be checked distally. Bleeding on        the scalp is best controlled by suturing of the wound. For extremities, inflating a        blood pressure cuff above systolic pressure assists in wound inspection and repair.        However, be careful not to cause ischemic injury to the extremity.     B.Neurologic injury.        Check distal muscle strength and sensation. Always check sensation        before administering anesthesia. For hand and finger lacerations        check 2-point discrimination, which should be less than 1 cm at the fingertips.        A crush injury may also decrease 2-point discrimination. This may take several months        to recover. A lacerated nerve may be repaired immediately or have repair delayed. Loss        of sensation may be the first sign of a developing compartment syndrome.     C.Tendons.        Can be evaluated by inspection, but individual muscles must also be tested for        full range of motion and full strength.     D.Bones.        Check for open fracture or associated fractures. X-ray if any question.        An open fracture is an indication for surgical debridement and repair except        in the case of a distal phalanx fracture where copious irrigation and        oral antibiotics are acceptable treatment if the injury can be watched carefully for infection.     E.Foreign bodies.        Inspect and x-ray the area. Remember that wood or low-lead glass may not show on radiograph.        Wound markers can be used during radiographing, and views obtained in two planes can help        localize the object for recovery. Glass may penetrate at an angle and be buried deeper than        it appears to be.        Ultrasonography is very sensitive at picking up foreign bodies if radiograph is questionable        or there is strong clinical suspicion. ***IV.Repair     A. Wound healing.        1.Ephithelialization occurs in 24-48 hours under optimal conditions.        2.Collagen formation. Peaks at day 7. Wound has 15% to 20% of full strength at 3 weeks,         60% full strength at 4 months. The wound is then completely sealed.        3.Scar formation. Requires 6 to 12 months for a mature scar. The smallest scar will be         formed when the wound is not under tension. Scars should not be revised until 12 months         have passed. Contractures can develop when a scar intersects perpendicularly to a joint crease. Wound preparation. Hand washing, face masks are recommended. ANESTHESIA 1. In general, pain control should be provided before extensive wound preparation. 2. Local. Use 27- or 30-gauge needle and infiltrate slowly and through the open wound edge avoiding the intact skin. This decreases the pain of infiltration. The addition of bicarbonate to lidocaine before infiltration has been shown to significantly decrease the pain of injection (9 ml of lidocaine and 1 ml of bicarbonate) and warming lidocaine to body temperature may help as well. a.Lidocaine (0.5% to 2%) most frequently used with onset 2 to 5 minutes, duration 60 minutes. Can use 3 to 5 mg/kg with not more than 300 mg total (in adults). Avoid using lidocaine with epinephrine on distal extremities such as the ears, fingers, toes, and penis. b.Mepivacaine (Carbocaine) has onset 3 to 5 minutes, duration of 90 to 120 minutes. c.Bupivacaine (Marcaine) has onset 5 to 10 minutes, duration of hours; longest lasting of the local anesthetics. Intravenous administration may cause serious arrhythmias. d.For "caine" allergies, use diphenhydramine diluted to 1%. Mix 5% diphenhydramine 1:4 ml with normal saline to make a 1% solution. Onset of anesthesia takes longer and does not last so long as with lidocaine. Stronger solutions may cause tissue necrosis. 3. Regional anesthesia. Especially good for fingers, hands, feet, toes, mouth, and face. See Chapter 17 for common blocks.   HEMOSTASIS Control of bleeding is necessary for both hemodynamic stability and for proper evaluation of a wound. Direct pressure, epinephrine, bipolar electrocautery, tourniquet. FOREIGN -BODY REMOVAL Avoid the temptation to initially explore wounds with a finger in search of foreign body. Plain radiography , US, CT HAIR REMOVAL Shaving the area with a razor damage the hair follicle, allowing bacterial invasion, and is associated with a ten fold increase in infection rate when compared with clipping. Hair should be as completely as possible with clipping 1to 2 mm above the skin with scissors. Never shave eyebrows because they are needed for alignment of the wound and may not grow back. IRRIGATION Irrigation pressures of 5 to 8 psi are recommended, which is achieved using a 19-guage needle with either 35-ml or 65-ml syringe. Fluid (saline) volume : 60ml /cm of wound length. 200ml-1000ml. There is no added benefit to the addition of an antiseptic ( such as povidone-iodine or hydrogen peroxide) . All detergents cause tissue and fibroblast toxicity.   DEBRIDEMENT Not only removes foreign matters, bacteria, and devitalized tissue, but also creates a sharp wound edge that is easier to repair. Using aseptic technique, devitalized tissue should be removed; avoid taking healthy tissue. High-pressure irrigation is the most effective means of cleansing a wound. Scrubbing does not cleanse the wound as well and using any disinfectant in the wound damages healthy cells needed for healing. SKIN DISINFECTION Can be performed with povidone-iodine solution or chlorhexidine. Avoid getting these solutions in the wound because they impede wound healing. D. Wound closure. 1.Avoid primary closure of infected and inflamed wounds, dirty wounds, human and animal bites, neglected and severe crush wounds,and puncture wounds. 2.Tape closure (with Steri-Strips or others). Strips carry a lower risk of infection than suturing does and may be a consideration for higher-risk wounds. 3.Open wound care. Saline wet to dry dressings with gauze will keep the tissue moist and help debride, Gentle washing of the wound 2 to 3 times per day will remove bacterially contaminated secretions (showers are appropriate for this). Avoid iodine dressings because they damage healthy tissue and will slow granulation. When clean granulation tissue is apparent, secondary closure may be considered or can change to dry, sterile, packing material. 4.Suturing. Sutures are of two types: (1) absorbable and (2) nonabsorbable. Precision-point cutting needles, and small-sized suture (5-0 or 6-0) should be chosen for skin when a cosmetic closure is important as on the face. Conventional cutting needle is used for routine skin closure. 4-0 or 3-0 nylon may be used on extremities. Noncutting needle should be used for subcutaneous tissue. Extensor tendons are slow healing and should have permanent suture of small size chosen (such as polypropylene). Depending on your practice situation, a surgical consultation should be considered. The majority of subcutaneous or dermal suturing may be performed with an intermediate-duration absorbable suture. However, some wounds require permanent sutures (such as stainless steel wires in sternotomy). 5.Staples. Can be used on the scalp and abdomen with good result. However, avoid use on face, hand, or other areas where structures such as tendons and nerves may become incorporated into the staples. 6.Dressings. Maintaining a moist environment for the first 24h-48 h facilitate healing. Dressing absorbs exudate, protect contamination, and prevention of premature removal. Consider antibiotic petroratum-based ointment on face and torso. Antibiotic ointment should be avoided on distal extremities for more than 24 to 48 hours because it may lead to maceration and delayed wound healing. Immobilize if motion of a joint is going to increase skin tension. Keep the wound for 24 hours, after which time most wounds do not require a dressing. 7.Antibiotics. There is no medical indication for using prophylactic antibiotics in routine, noncontaminated, skin wounds. a.Consider antibiotic use for patients prone to endocarditis, patients with hip prostheses, lymphedema, contaminated foot wound in diabetics, or others with peripheral vascular disease. b. See Chapter 1 for antibiotic choices for bite wounds.   ***V.Follow-Up Care A. Risk of infection highest 24 to 48 hours, and so all wounds should be rechecked at 48h. B.Washing and Grooming Within 8 to 24h after closure, wounds in highly vascular areas can be washed. Other areas can be washed after 12-24h without increased an adverse outcome. However, immersion or soaking should be avoided. C.General guidelines for suture removal. Face, 3 to 5 days with tape reinforcement after suture removal. Scalp, 7 to 10 days; trunk, 7 to 10 days; arms, 7 to 10 days; legs, 10 to 14 days; joints, dorsal surface, 14 days. Increase length for diabetics or steroid-dependent patients who may require several weeks to heal.
*Wound Management nishitarumizu          2000.9.19 ***I. General Principles     The goal of wound management is primarily restoration of function, which requires minimizing    risk of infection and repair of injured tissue with a minimum of cosmetic deformity. Be sure to    maintain universal precautions.   ***II. Significant History   A. Mechanism of injury.      1.Blunt trauma. Split or crush type of injuries will swell more and tend to have more       devitalized tissue and a higher risk of infection.      2.Sharp trauma. Clean edges, low cellular injury, and risk of infection.      3.Puncture wounds.      4.Bite injury.   B.Contaminants.      Wound contact with manure, rust, dirt, etc., will increase risk of infection.      Wounds sustained in barnyards or stables are considered contaminated.      Clostridium tetani is indigenous in manure.   C.Time of injury.      After 3 hours, the bacterial count in a wound increases dramatically.Wounds may be closed       primarily up to 12-18 hours out; clean well and use clinical judgment when choosing which       wounds to close.      Wounds up to 24 hours old on the face may be closed after good cleaning. The blood supply      in this area is much better and the risk of infection therefore much less.      The risk of infection may be reduced in wounds by use of tape closures (such as Steri-Strip      tape).   D.[[Tetanus status(http://homepages.go.com/homepages/a/n/e/anealkhan/tetanus_prophylaxis.htm)>http://homepages.go.com/homepages/a/n/e/anealkhan/tetanus_prophylaxis.htm]]   E.Other medical illnesses.      Diabetes, chemotherapy, steroids, peripheral vascular disease, and malnutrition may delay      wound healing and increase the risk of infection.   ***III.Physical Exam     A.Vascular injury.        Direct pressure is the first choice for controlling bleeding.        If a fracture is involved, immobilization will help control bleeding. Do not clamp        vascular structures until it is determined if it is a significant vessel needing repair.        If the anatomy is suspicious for injury to major vascular structures, obtain angiogram        and consider surgical consult. Capillary refill should be checked distally. Bleeding on        the scalp is best controlled by suturing of the wound. For extremities, inflating a        blood pressure cuff above systolic pressure assists in wound inspection and repair.        However, be careful not to cause ischemic injury to the extremity.     B.Neurologic injury.        Check distal muscle strength and sensation. Always check sensation        before administering anesthesia. For hand and finger lacerations        check 2-point discrimination, which should be less than 1 cm at the fingertips.        A crush injury may also decrease 2-point discrimination. This may take several months        to recover. A lacerated nerve may be repaired immediately or have repair delayed. Loss        of sensation may be the first sign of a developing compartment syndrome.     C.Tendons.        Can be evaluated by inspection, but individual muscles must also be tested for        full range of motion and full strength.     D.Bones.        Check for open fracture or associated fractures. X-ray if any question.        An open fracture is an indication for surgical debridement and repair except        in the case of a distal phalanx fracture where copious irrigation and        oral antibiotics are acceptable treatment if the injury can be watched carefully for infection.     E.Foreign bodies.        Inspect and x-ray the area. Remember that wood or low-lead glass may not show on radiograph.        Wound markers can be used during radiographing, and views obtained in two planes can help        localize the object for recovery. Glass may penetrate at an angle and be buried deeper than        it appears to be.        Ultrasonography is very sensitive at picking up foreign bodies if radiograph is questionable        or there is strong clinical suspicion. ***IV.Repair     A.Wound healing.       1.Ephithelialization occurs in 24-48 hours under optimal conditions.       2.Collagen formation. Peaks at day 7. Wound has 15% to 20% of full strength at 3 weeks,         60% full strength at 4 months. The wound is then completely sealed.       3.Scar formation. Requires 6 to 12 months for a mature scar.         The smallest scar will be formed when the wound is not under         tension. Scars should not be revised until 12 months         have passed. Contractures can develop when a scar intersects         perpendicularly to a joint crease.     B.Wound preparation.       Hand washing, face masks are recommended.     C.ANESTHESIA       1.In general, pain control should be provided before extensive        wound preparation.       2.Local. Use 27- or 30-gauge needle and infiltrate slowly and        through the open wound edge avoiding the intact skin.        This decreases the pain of infiltration. The addition of        bicarbonate to lidocaine before infiltration has been shown to        significantly decrease the pain of injection (9 ml of lidocaine        and 1 ml of bicarbonate) and warming lidocaine to body temperature        may help as well.         a.Lidocaine (0.5% to 2%) most frequently used with onset 2 to 5          minutes, duration 60 minutes. Can use 3 to 5 mg/kg with not          more than 300 mg total (in adults). Avoid using lidocaine with          epinephrine on distal extremities such as the ears, fingers,          toes, and penis.         b.Mepivacaine (Carbocaine) has onset 3 to 5 minutes, duration of          90 to 120 minutes.         c.Bupivacaine (Marcaine) has onset 5 to 10 minutes, duration of          hours; longest lasting of the local anesthetics. Intravenous          administration may cause serious arrhythmias.         d.For "caine" allergies, use diphenhydramine diluted to 1%.          Mix 5% diphenhydramine 1:4 ml with normal saline to make a          1% solution. Onset of anesthesia takes longer and does not          last so long as with lidocaine. Stronger solutions may cause          tissue necrosis.       3. Regional anesthesia. Especially good for fingers, hands, feet,         toes, mouth, and face. See Chapter 17 for common blocks.         HEMOSTASIS          Control of bleeding is necessary for both hemodynamic         stability and for proper evaluation of a wound.          Direct pressure, epinephrine, bipolar electrocautery,         tourniquet.       FOREIGN -BODY REMOVAL          Avoid the temptation to initially explore wounds with a finger         in search of foreign body. Plain radiography , US, CT       HAIR REMOVAL          Shaving the area with a razor damage the hair follicle,         allowing bacterial invasion, and is associated with a ten fold         increase in infection rate when compared with clipping. Hair         should be as completely as possible with clipping 1to 2 mm above         the skin with scissors.          Never shave eyebrows because they are needed for alignment of         the wound and may not grow back.       IRRIGATION          Irrigation pressures of 5 to 8 psi are recommended, which is         achieved using a 19-guage needle with either 35-ml or 65-ml         syringe.          Fluid (saline) volume : 60ml /cm of wound length. 200ml-         1000ml.          There is no added benefit to the addition of an antiseptic (         such as povidone-iodine or hydrogen peroxide) . All detergents         cause tissue and fibroblast toxicity.         DEBRIDEMENT          Not only removes foreign matters, bacteria, and devitalized         tissue,but also creates a sharp wound edge that is easier to         repair.          Using aseptic technique, devitalized tissue should be removed;         avoid taking healthy tissue. High-pressure irrigation is the         most effective means of cleansing a wound. Scrubbing does not         cleanse the wound as well and using any disinfectant in the         wound damages healthy cells needed for healing.       SKIN DISINFECTION          Can be performed with povidone-iodine solution or         chlorhexidine.              Avoid getting these solutions in the wound because they impede         wound healing.     D.Wound closure.       1.Avoid primary closure of infected and inflamed wounds, dirty         wounds, human and animal bites, neglected and severe crush           wounds,and puncture wounds.       2.Tape closure (with Steri-Strips or others). Strips carry a lower         risk of infection than suturing does and may be a consideration         for higher-risk wounds.       3.Open wound care. Saline wet to dry dressings with gauze will keep         the tissue moist and help debride, Gentle washing of the wound 2         to 3 times per day will remove bacterially contaminated         secretions (showers are appropriate for this). Avoid iodine         dressings because they damage healthy tissue and will slow         granulation. When clean granulation tissue is apparent,         secondary closure may be considered or can change to dry,         sterile, packing material.       4.Suturing.         Sutures are of two types: (1)absorbable and (2)nonabsorbable.         Precision-point cutting needles, and small-sized suture (5-0 or         6-0) should be chosen for skin when a cosmetic closure is         important as on the face. Conventional cutting needle is used         for routine skin closure.         4-0 or 3-0 nylon may be used on extremities.         Noncutting needle should be used for subcutaneous tissue.         Extensor tendons are slow healing and should have permanent         suture of small size chosen (such as polypropylene).         Depending on your practice situation, a surgical consultation         should be considered.         The majority of subcutaneous or dermal suturing may be performed         with an intermediate-duration absorbable suture. However, some         wounds require permanent sutures (such as stainless steel wires         in sternotomy).       5.Staples.         Can be used on the scalp and abdomen with good result.         However, avoid use on face, hand, or other areas where         structures such as tendons and nerves may become incorporated         into the staples.       6.Dressings.         Maintaining a moist environment for the first 24h-48 h         facilitate healing. Dressing absorbs exudate, protect         contamination, and prevention of premature removal.         Consider antibiotic petroratum-based ointment on face and torso.         Antibiotic ointment should be avoided on distal extremities for         more than 24 to 48 hours because it may lead to maceration and         delayed wound healing.         Immobilize if motion of a joint is going to increase skin         tension.         Keep the wound for 24 hours, after which time most wounds do not         require a dressing.       7.Antibiotics.         There is no medical indication for using prophylactic         antibiotics in routine, noncontaminated, skin wounds.          a.Consider antibiotic use for patients prone to endocarditis,            patients with hip prostheses, lymphedema, contaminated foot            wound in diabetics, or others with peripheral vascular            disease.          b.See Chapter 1 for antibiotic choices for bite wounds.   ***V.Follow-Up Care     A.Risk of infection highest 24 to 48 hours, and so all wounds should       be rechecked at 48h.     B.Washing and Grooming Within 8 to 24h after closure, wounds in highly       vascular areas can be washed. Other areas can be washed after 12-       24h without increased an adverse outcome. However, immersion or       soaking should be avoided.     C.General guidelines for suture removal. Face, 3 to 5 days with tape       reinforcement after suture removal. Scalp, 7 to 10 days; trunk,       7 to 10 days; arms, 7 to 10 days; legs, 10 to 14 days; joints,       dorsal surface, 14 days. Increase length for diabetics or       steroid-dependent patients who may require several weeks to heal.

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